Newborn screening by MS/MS

Extended Newborn screening using MS/MS methodology

Targeted MS/MS Hemo for the screening of hemoglobinopathies

The Targeted MS/MS Hemo assay is an analytical sample processing assay for the detection of peptides from normal and variant haemoglobins in neonates using blood spots samples dried on filter paper. The assay principle is based on a rapid extraction of haemoglobin from blood spot before its enzymatic digestion and analysis by mass spectrometry (flow injection analysis). This process allows the discrimination of different peptides (wild or mutated) for the haemoglobinopathies screening, i.e. α- and β- thalassaemias and globin variants.

Benefits of the kit

• Allow differenciation between Heterozygous & Homozygous status
• Multriplex several pathologies in one well
• Compatible with various TQ Mass Spectrometer
• Include easy-to-use software for data analysis