Immunoassay
The NEONATAL Biotinidase Screening Assay kit is an enzymatic test for biotinidase activity quantification. This test is intended for neonatal screening of biotinidase (BTD) deficiency and is performed using dried blood samples on 903® or 226 blotting paper.
Serum biotinidase (BTD) activity measurement
The kit is based on a catalysis reaction of biotinidase extracted from the sample. In the presence of an artificial substrate, biotinidase will release 4-aminobenzoic acid (PABA). After discontinuation of the reaction by denaturation of biotinidase, the generated PABA will react with sodium nitrite to form a diazotized compound. The purple coloration obtained can be directly measured by absorption and is directly proportional to the biotinidase activity in the sample.
The kit allows neonatal screening of biotinidase deficiency in newborns
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The NEONATAL TOTAL-T4 Screening ELISA kit is an ELISA-type quantitative hypothyroidism test used to quantify the totality of thyroxine (T4) contained in a test dried blood samples on 903® or 226 blotting paper. This test is for congenital hypothyroidism newborn screening.
The Immunomat™ is intended for neonatal screening laboratories performing between 400 and 1000 daily determinations. With a maximum capacity of 7 microplates, it optimizes the rate of the laboratory by allowing the processing of different parameters in parallel.