Fluorometry
The NEONATAL G-6-PD Screening Fluo device uses fluorescence detection to quantify the activity of the enzyme Glucose-6-Phosphate Dehydrogenase (G-6-PD) as part of the newborn screening for G6PD deficiency. This test is designed to be performed blood samples from newborns dried on 903 or 226 filter paper.
G-6-PD extracted from the newborn sample catalyzes, in the presence of NADP+, the oxidation of glucose-6-phosphate and induces the formation of NADPH. NADPH is a fluorescent molecule that, after being excited at a wavelength of 355 nm, emits a signal at a wavelength of 460 nm that is proportional to the enzymatic activity of G6PD.
This assay is designed to detect Glucose-6-Phosphate deficiency (or favism) in newborns from a dried blood sample on blotting paper type 903® or 226.
Product code
The NEONATAL G-6-PD Screening Assay is an enzymatic test in newborns for the quantification of glucose-6-phosphate dehydrogenase (G-6-PD) activity. This test is intended for neonatal screening of favism or glucose-6-phosphate dehydrogenase (G-6-PD) deficiency in newborns and is performed using dried blood samples on 903® or 226 blotting paper.